Effect of Lindane in Steroidogenesis and Testis Tissues
نویسندگان
چکیده
Present study to investigate the effects of lindane in steroidogenesis and testis tissues of adult male albino rat. Adult male rats were orally administered with lindane at a dose of 5.0mg/kg body weight per day for 30 days, the rat were killed using anesthetic ether, plasma was collected and testis were removed histopathological studies. Male albino rats were treated with lindane, decreased the fertilility hormone such as testosterone, LH, FSH and estradiol. Lindane alter fertility hormone and altered the biochemical parameter such as protein, cholesterol, lipid profile. A histopathological analysis of testicular tissue from treated rats showed cell disorganization. Cells were irregularly shaped, with marked intercellular space between the spermatogenic cells were observed. Our results imply that organochlorine insecticides like lindane can cause reproductive disorders, and therefore more attention should be directed towards understanding the affects of persistent pesticide residues on reproductive outcomes. © 2014 Universal Research Publications. All rights reserved.
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